- Moderate to severe pneumonia:
- IV 2g TDS *7/7
- Febrile neutropenia:
- IV 2g TDS * 7/7 or until neutropenia resolves
- UTI:
- Uncomplicated: IV 0.5-1g BD *7-10 days
- Complicated: IV 2g BD *7-10 days
- Uncomplicated skin & soft tissue infections:
- IV 2g BD *10/7
- Intra-abdominal infections (in combination with metronidazole):
- IV 2g BD *10/7
- Children > 2 months: 50mg/kg/dose BD/TDS. Max 2g/dose
Injection:
- 500mg
- 1g
- 2g
- To be reconstituted with 50-100 mL of NS, D5W, D10W, LR, D5/LR or other compatible fluid
- Stored at room temperature
- IV infusion to be given over 30 minutes
- May become darker after mixing with a diluent.
4th generation cephalosporin.
Bactericidal. It inhibits synthesis of bacterial cell wall. Best beta-lactam against Gram +ve and beta lactamase producing bacteria and for IM administration. It has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis.
- Injection site reaction
- Diarrhoea
- Rash
- Pseudomembranous colitis
- Hypophosphatemia
- Eosinophilia
- Fever
- Headache
- Oral moniliasis
- Anaemia
- Hypersensitivity to compound/class
- Live attenuated vaccines
- Bumetanide
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Can be used |
| Breastfeeding | Can be used |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Cefepimark | 1g | Injection | 1’s | Marksans Pharma | Sai Pharma |
| Ceficad | 2g | Injection | 1’s | Cadila Pharm | Cadila Pharm |
| Ceficad | 1g | Injection | 1’s | Cadila Pharm | Cadila Pharm |
| Ceftipime | 500mg | Injection | 1’s | Renata Limited | Harley’s Ltd |
| Ceftipime | 1g | Injection | 1’s | Renata Limited | Harley’s Ltd |
| Ceftipime | 2g | Injection | 1’s | Renata Limited | Harley’s Ltd |
| Inno-Pime | 1g | Injection | 1’s | Innocia Lifesciences | Wessex Pharma |
| Megapime | 1g | Injection | 1’s | Alkem Labs | Pharmacor Ltd |
| Pimcef | 1g | Injection | 1’s | Venus Remedies | Surgipharm Ltd |
| Pozineg | 1g | Injection | 1’s | Aurobindo Pharma | Aurobindo Pharma |
| Totacef | 1g | Injection | 1’s | Mankind Pharma | Surgilinks Ltd |