- Edema in patients with CHF, hepatic disease or renal disease:
- Initially PO 20-80mg *1, increased by 20-40mg every 6-8 hours
- Max: 600mg/day
- Initially PO 20-80mg *1, increased by 20-40mg every 6-8 hours
-
- IV/IM 20-40mg *1, may be increased by 20mg every 2 hours
- Individual dose not to exceed 200mg/dose
- Individual dose not to exceed 200mg/dose
- IV/IM 20-40mg *1, may be increased by 20mg every 2 hours
- Acute pulmonary edema, hypertensive crisis, increased intracranial pressure:
- IV 40mg *1
- May be increased to 80mg if no adequate response within 1 hour
- Max 160-200 mg/dose
- IV 40mg *1
- Resistant hypertension:
- PO 20-80mg divided BD
- PO 20-80mg divided BD
- Hyperkalemia in Advanced Cardiac Life Support
- IV 40-80mg
- IV 40-80mg
- Hypermagnesemia in Advanced Cardiac Life Support
- IV 20-40mg every 3-4 hours PRN
- IV 20-40mg every 3-4 hours PRN
- Hypercalcemia (Off-label):
- PO 120mg/day divided OD/TDS
-
- IM/IV 80-100mg every 1-2 hours
- Given with saline
- IM/IV 80-100mg every 1-2 hours
Injection: 10mg/mL
Tablet: 40mg
None remarkable
Loop diuretic
It inhibits reabsorption of sodium and chloride ions at proximal and distal renal tubules and loop of Henle by interfering with chloride-binding cotransport system
- Urinary frequency
- Dizziness
- Nausea & vomiting
- Weakness
- Muscle cramps
- Hypokalemia
- Hypomagnesemia
- Orthostatic hypotension
- Elevated ALT/AST
- Blurred vision
- Anorexia
- Abdominal cramps
- Diarrhea
- Pruritus
- Rash
- Hyperuricemia
- Hyperglycemia
- Hypocalcemia
- Tinnitus
- Paresthesia
- Photosensitivity
- Increased cholesterol
- Increased triglycerides
- Hypersensitivity to furosemide or sulfonamides
- Anuria
- Hepatic coma
- Electrolyte imbalances
WARNING
It is a potent diuretic and in excessive amounts can cause profound diuresis with water/electrolyte depletion
- Desmopressin
- Isocarboxazid
Drug Status
| Availability | Prescription only |
| Pregnancy | Category C |
| Breastfeeding | Not recommended; inhibits lactation |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Asix | 40mg | Tablet | 100’S | Opera Pharma | Opera Pharma |
| Carefusem | 40mg | Tablet | 100’s | Careplus Ltd | Careplus Ltd |
| Diasix | 20mg/2mL | Injection | 10’s | Lincoln Pharma C/O Medox Pharma | Medox Pharma |
| Diuresal | 40mg | Tablet | 24’s | Lagap SA | Lagap SA |
| Fruseberg | 10mg/mL | Injection | 10’s | Sunberg Lifesciences | Synermed Pharma |
| Frusemide | 20mg/2mL | Injection | 10’s | Crown Healthcare | Crown Healthcare |
| Frusemide | 20mg/2mL | Injection | 10’s | Laboratoire Renaudin | Nairobi Pharma |
| Frusemide | 40mg | Tablet | 100’s, 1000’s | Dawa Ltd | Dawa Ltd |
| Frusemide | 20mg/2mL | Injection | 10’s | Dawa Ltd | Dawa Ltd |
| Frusemide | 40mg | Tablet | 100’s | Gracure Pharma | Medisel Kenya |
| Frusemide | 40mg | Tablet | 100’s | Elys Chemical | Elys Chemical |
| Frusemide | 10mg/2mL | Injection | 10’s | Questa Care C/O Surgilinks Ltd | Surgilinks Ltd |
| Frusemide | 40mg | Tablet | 100’s, 1000’s | Biodeal Labs | Biodeal Labs |
| Frusemide | 40mg | Tablet | 100’s | Laboratory & Allied | Laboratory & Allied |
| Fruz | 20mg | Injection | 10’s | Zawadi Healthcare | Zawadi Healthcare |
| Fruz | 40mg | Tablet | 100’s | Biopharma Ltd | Biopharma Ltd |
| Furo-Denk | 40mg | Tablet | 100’s | Denk Pharma | Laborex Kenya |
| Furomed | 10mg/mL | Injection | 10’s | Medisel Kenya | Medisel Kenya |
| Furosemide | 40mg | Tablet | 100’s | Sandoz GMBH | Novartis Kenya |
| Furosemide | 40mg | Tablet | 100’s | Medopharm C/O Medox | Medox Pharma |
| Furosemide | 40mg | Tablet | 100’s | Cosmos Ltd | Cosmos Ltd |
| Fusid | 20mg/2mL | Injection | 10’s | Square Pharma | Ace Pharma |
| Fusid | 40mg | Tablet | 100’s | Square Pharma | Ace Pharma |
| Lasideal | 40mg | Tablet | 100’s, 1000’s | Biodeal Labs | Biodeal Labs |
| Lasix | 20mg/2mL | Injection | 5’s | Sanofi-Aventis | Ressourcethica Kenya |
| Lasix | 40mg | Tablet | 20’s | Sanofi-Aventis | Ressourcethica Kenya |
| Pharmacare | 20mg/2mL | Injection | 10’s | KNVM Medicare | KNVM Medicare |
| Tasix | 10mg/mL | Injection | 10’s | Tasa Pharma | Tasa Pharma |
| Unosemide | 10mg/mL | Injection | 10’s | Unosource Pharma | Unisel Ltd |