- General anesthesia induction:
- 5-3% can produce surgical anesthesia in 7-10 minutes
- General anesthesia maintenance:
- 1-2.5% with nitrous oxide or 1.5-3% with oxygen only
Inhalation vapour: 250mL
None remarkable
General anesthetic
It is thought to alter neuronal ion channels such as GABA, glutamate and glycine receptors, resulting in decreased tissue excitability
- Agitation
- Cough
- Shivering
- Nausea
- Vomiting
- Laryngospasm
- Post-anesthetic delirium
- Psychomotor slowing
- Uterine relaxation
- Respiratory depression
- Hypotension
- Arrhythmia
- Hypersensitivity to drug/components
- History of malignant hyperthermia
- Halogenated anesthesia-associated hepatitis
- Moderate-severe halogenated anesthesia-associated hepatic impairment
- Cisapride
- Dronedarone
- Levoketoconazole
- Pimozide
- Thioridazine
Drug Status
| Availability | Prescription only |
| Pregnancy | Category C |
| Breastfeeding | Unknown; use with caution |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Forane | 250mL | Inhalation solution | 1’s | Abbvie | Phillips Therapeutics |
| Isoflurane | 250mL | Inhalation solution | 1’s | Piramal Enterprises | Galaxy Pharma |
| Isotroy | 250mL | Inhalation solution | 1’s | Troikaa | Harley’s Ltd |