• Hypertension:
    • 1 tab OD

Tablet:

  • 5mg/160mg/12.5mg
  • 10mg/160mg/12.5mg
  • Should NOT be used as the initial treatment
  • Dose may be increased every 2 weeks

Amlodipine: Dihydropyridine, calcium channel blocker

Valsartan: Angiotensin II receptor (ARB) blocker

Hydrochlorothiazide: Thiazide diuretic

  • Dizziness
  • Peripheral edema
  • Headache
  • Dyspepsia
  • Fatigue
  • Muscle spasms
  • Back Pain
  • Nausea
  • Nasopharyngitis
  • Elevated BUN or Cr
  • Increase ALT/AST
  • Hyperglycemia
  • Hyperlipidemia
  • Hyperuricemia
  • Eczematous eruptions (chronic use in elderly patients)
  • Hypersensitivity to components or sulphonamides
  • Anuria
  • Pregnancy
  • Breastfeeding (HCTZ dose >50 mg/day)
  • CrCl <10
  • ACEIs
  • Lithium
  • Amikacin
  • Lithium
  • Erythromycin
  • Halofantrine
  • Pentamidine
  • Terfenadine
  • Mannitol

                                   Drug Status

Availability Prescription only
Pregnancy Category D
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Exforge HCT 10mg/160mg/12.5mg Tablet 28’s Novartis Pharma Novartis Kenya
Exforge HCT 5mg/160mg/12.5mg Tablet 28’s Novartis Pharma Novartis Kenya